Charlotte finished in second place at 15-under, and Toledo and Augusta finished T3 at 2-under.
ETSU, winners in 2018 and 2021, entered the day with a three-shot lead and used the final round to run away from the field.
ETSU shot 14-under 274 in the final round, marking the second straight day they posted the low round.
Ege, who captured his third collegiate win, started with his historic round on Sunday and was never caught. Ege fired a tournament, course, and school record 10-under 62 in round one.
Ege missed tying the overall tournament record by one shot. Ege finished the tournament with 18 birdies.
Overall, Ege and Kleen combined to shoot 27-under with 33 birdies for the tournament. Ege led the field in par-4 scoring at 6-under, and par-5 scoring at 11-under.
Kleen was second in par-3 scoring at 3-under, and par-5 scoring at 8-under.
Conor Gough of Charlotte and Joe Sullivan of Florida Gulf Coast finished T3 at 5-under.
